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1.
Hand (N Y) ; 18(2): 250-253, 2023 03.
Artigo em Inglês | MEDLINE | ID: mdl-34078170

RESUMO

BACKGROUND: Trigger finger is a common hand complaint of the general population. Limited literature exists implicating a low-estrogen state in patients on aromatase inhibitor (AI) therapy for breast cancer who develop trigger finger. The authors' objective was to determine the incidence and treatment outcomes of this population. METHODS: A single-center retrospective chart review was conducted on patients with a diagnosis of breast cancer on AI who developed trigger finger from 2010 to 2019. The total population of patients during this time served as our population, and patients with breast cancer not on AI with trigger finger served as our control. Primary outcomes included total number of injections and need for surgery. Secondary outcomes included risk factors for surgery. χ2 analysis and logistical regression model determined the significance of primary and secondary outcomes, respectively. RESULTS: In all, 192 patients of a population size of 664 751 met our study group criteria. The study group showed a higher incidence of trigger finger (5.1% vs 1.3%; P < .001) compared with our population. Patients treated with AI for breast cancer had both higher incidence of trigger finger (5.1% vs 1.5%, P < .001) and injections (77.1% vs 66.5%, P < .001) compared with patients not on AI therapy. Independent risk factors requiring surgical treatment were found in patients with diabetes (odds ratio [OR], 3.54; P = .01) and in patients with concomitant radiation therapy (OR, 3.17; P = .02). CONCLUSIONS: This study demonstrates for the first time the incidence, treatment outcomes, and surgical risk factors of trigger finger in patients on AI therapy for breast cancer.


Assuntos
Neoplasias da Mama , Dedo em Gatilho , Humanos , Feminino , Neoplasias da Mama/tratamento farmacológico , Neoplasias da Mama/induzido quimicamente , Inibidores da Aromatase/efeitos adversos , Estudos Retrospectivos , Dedo em Gatilho/terapia , Dedo em Gatilho/cirurgia , Incidência , Resultado do Tratamento
4.
J Craniofac Surg ; 27(8): e785-e787, 2016 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-28005824

RESUMO

Craniofacial clefts are rare entities, with an incidence reported as 1.43 to 4.85 per 100,000 births. The Tessier number 3 cleft, the most medial of the oblique clefts, can manifest as clefting of the lip between the canine and lateral incisors, colobomas of the nasal ala and lower eyelid, and inferior displacement of the medial canthus-frequently disrupting the lacrimal system with extreme variability in expressivity (Eppley).Literature on cleft lip repair is extensive and has evolved to incorporate anthropometric techniques, based on identifiable landmarks and anthropometric measurements that are compared with contralateral unaffected anatomy or population means and tracked over time to assess impact on growth. Recent focus has been placed on "subunit" repair that repairs "like with like." These approaches have resulted in a remarkable reproducibility of methods and outcomes.Facial cleft surgery publications are sparse due to the rarity of the disorders, and consensus has yet to develop on standardized landmarks, reference measurements, and principles of repair. The authors describe a method of correcting incomplete unilateral Tessier 3 cleft based on the principles described above. Intraoperative photographs, including secondary revisions, as well as immediate and long-term postoperative results are presented.


Assuntos
Anormalidades Múltiplas/cirurgia , Fenda Labial/cirurgia , Coloboma/cirurgia , Anormalidades Craniofaciais/cirurgia , Pálpebras/anormalidades , Nariz/anormalidades , Procedimentos de Cirurgia Plástica/métodos , Anormalidades Múltiplas/diagnóstico , Antropometria , Criança , Pré-Escolar , Fenda Labial/diagnóstico , Coloboma/diagnóstico , Anormalidades Craniofaciais/diagnóstico , Pálpebras/cirurgia , Humanos , Lactente , Masculino , Nariz/cirurgia , Resultado do Tratamento
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